| 摘要 |
Promotant comprises microgranules having a core consisting of one or more enzymes selected from: (i) protein digesting enzymes, (ii) carbohydrate digesting enzymes, (iii) fat digesting enzymes and (iv) fibre digesting enzymes, the core being encapsulated within a water soluble film and coated with an enteric coating comprising an alkali soluble, acid insoluble polymer or a high mol. wt. polymer whose structure is substd. with or contains windows of fatty acid or other material capable of being solubilised by intestinal juices. Pref. the core comprises enzyme(s) immobilised within a gel-like matrix of e.g. K-carrageenan, gelatin, alginates, cellulose or its derivs. or gel forming synthetic polymers. Pref. the water soluble film is gelatin and the alkali soluble acid insoluble polymer is cellulose acetate phthalate. The high mol. wt. polymer is pref. butyl methacrylate.
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