| 发明名称 |
Process for production of human nerve growth factor by genetic engineering. |
| 摘要 |
<p>By culturing E. coli carrying DNA encoding human nerve growth factor (hNGF) in a medium supplemented with 3-ss-indolylacrylic acid or containing no tryptophan, hNGF can be easily obtained as a fused protein in large quantities with a high efficiency. hNGF is applicable for the treatment of neuropathy. <IMAGE></p> |
| 申请公布号 |
EP0458437(A1) |
申请公布日期 |
1991.11.27 |
| 申请号 |
EP19910301386 |
申请日期 |
1991.02.21 |
| 申请人 |
HITACHI, LTD. |
发明人 |
SHIMIZU, NORIO;FUJIMORI, KIYOSHI;FUKUZONO, SHINICHI;KOTOMURA, NAOE |
| 分类号 |
C12N1/21;C07K14/48;C12N1/11;C12N15/12;C12P21/02;C12R1/19 |
主分类号 |
C12N1/21 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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