Polymer-combined drug and a method for producing the drug.
摘要
<p>The present invention provides a polymer-combined drug having directional characteristics to digestive organs, wherein it comprises a medicine combined with a polymer which has an alkyleneoxy group as a repeating unit. The polymer-combined drug is produced by reacting a polyoxyalkylene glycol having one or more terminal functional groups and a medicine, if necessry in a solvent, and if necessary in the presence of a catalyst. It is able to administer the drug orally or by intravenous injection so as to maintain the concentration in blood stably for a long time, and to absorb or take in digestive organs such as the stomach and intestines directly.</p>
申请公布号
EP0452179(A2)
申请公布日期
1991.10.16
申请号
EP19910400815
申请日期
1991.03.26
申请人
NIPPON OIL AND FATS COMPANY, LIMITED;KOYAMA, YOSHIYUKI;KOJIMA, SHUJI