| 摘要 |
Compounds of formula (I) are disclosed, wherein R<1> is hydrogen, lower alkyl which may have one or more hydroxy, or aryl which may have suitable substituent(s), R<2> is hydrogen, hydroxy or protected hydroxy, R<3> is methyl, ethyl, propyl or allyl, R<4> is hydroxy or alkoxy, R<5> is oxo, (H, OH) or (H, alkoxy), X is oxo or (H, OH), n is an integer of 1 or 2, and the symbol of a line and dotted line is a single bond or a double bond, and salts thereof. And processes for their production, compositions containing them, and use as immunosuppressive agents are also described. |
