| 摘要 |
PURPOSE:To obtain a reproduced cellulose yarn dialysis membrane in which complement components are suppressed from being activated and which relieves temperature decrease of leucocytes by grafting acyl residues of polycarboxylic acid with >=0.1mg/1m<2> membrane surface area by esterification. CONSTITUTION:In a reproduced cellulose yarn dialysis membrane, acyl residues of polyethyleneglycol dicarboxylic or polyethyleneglycol monocarboxylate with 0.1mg/1m<2> membrane surface area are grafted by esterification at least on the membrane surface which contacts with blood. The reproduced cellulose yarn here means hollow yarn membrane having perfect circular cross-section, a few mum to 60mum of thickness, and 10mu to a few hundred mum of outer diameter. The estrification and grafting are carried out by treating the dialysis membrane with a treatment solution prepared by dispersing or dissolving an esterification catalyst as well as polycarboxylic acid or its derivative in a reaction medium. The resulting reproduced cellulose membrane suppresses complement components from being activated and relieves temporal decrease of leucocytes markedly to make the membrane economically and safely. |
