发明名称 INTERCALATING AGENTS
摘要 Compounds are disclosed having general formula (I), in which n is 1, 2 or 3; and R<1> and R<2> are each, independently, an ethyl, hydroxyethyl, or hydroxymethyl group; or R<1> and R<2>, together with the nitrogen atom to which they are attached, form a cyclic group which is a 1-piperidino, 2- or 4-(2-hydroxyethyl)-1-piperidino, 2-hydroxymethyl-1-piperidino, 4-(2-hydroxyethyl)- or 4-methyl-1-piperazino, or 4-morpholino group; or a pharmaceutically acceptable salt thereof. The compounds have utility as anti-cancer agents. A method of preparing the compounds, and pharmaceutical compositions containing the compounds, are also disclosed.
申请公布号 WO9100265(A1) 申请公布日期 1991.01.10
申请号 WO1990GB01004 申请日期 1990.06.29
申请人 CANCER RESEARCH TECHNOLOGY LTD. 发明人 NEIDLE, STEPHEN;JENKINS, TERENCE, CHARLES;AGBANDJE, MAVIS
分类号 C07C237/04;C07D211/22;C07D295/15 主分类号 C07C237/04
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