The invention relates to a novel immunogenic synthetic peptide that is capable of specifically blocking potassium channels of excitable membranes and inducing immunity against an effective lethal dose of Noxiustoxin. The invention also relates to the discovery that the immunogenic and blocking properties of the peptide are severable. Peptides possessing either the immunogenic or the blocking property are disclosed.
申请公布号
US4929718(A)
申请公布日期
1990.05.29
申请号
US19870132169
申请日期
1987.12.14
申请人
UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO
发明人
POSSANI, LOURIVAL D. P.;GURROLA, GEORGINA B.;BAYON, MARCO A. A. C.;SITGES, MARIA B.