发明名称 Imidazole derivatives and antimycotics containing them
摘要 New imidazole derivatives of the formula <IMAGE> (I) in which Ar denotes phenyl, biphenylyl, naphthyl or thienyl, each of which is optionally substituted by halogen, lower alkyl or lower alkoxy, R1 denotes hydrogen or lower alkyl, Alk denotes straight-chain or branched alkylene having 1 to 10 carbon atoms, Y denotes oxygen, sulfur, sulfinyl or sulfonyl, n denotes one of the numbers 0, 1 or 2, Z denotes sulfur or sulfinyl, m denotes the number 0 or 1, m being the number 0 when Y denotes sulfur, sulfinyl or sulfonyl, and m being the number 1 when Y denotes oxygen, and R2 denotes cyclohexyl, phenyl or naphthyl, each of which is optionally substituted by hydroxyl, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or denotes biphenylyl or pyridyl, and processes for their preparation. The imidazole derivatives have excellent antimycotic properties for use in human and veterinary medicine.
申请公布号 US4925855(A) 申请公布日期 1990.05.15
申请号 US19870137556 申请日期 1987.12.23
申请人 CL PHARMA AKTIENGESELLSCHAFT 发明人 SCHERMANZ, KARL;SAISCHEK, GERALD;URMANN, ROBERT;MARTETSCHLAGER, KURT
分类号 C07D233/60;A61K31/415;A61K31/4164;A61K31/44;A61K31/4427;A61K31/4433;A61P31/04;A61P31/10;C07D233/61;C07D401/12;C07D409/06;C07D521/00 主分类号 C07D233/60
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