摘要 |
<p>The invention relates to indoleacetic acid derivatives represented by general formula (I), [wherein X represents a piperidino group, a 1-pyrrolidinyl group or a 3-hydroxy-1-pyrrolidinyl group, Y represents α, (wherein R1 represents a hydrogen atom or a lower alkyl group, and $(1,3)$ represents 0, 1 or 2) or β, (wherein R2 represents a hydrogen atom, a lower akyl group or a hydroxy group, m represents 0, 1 or 2, and n represents 1, 2 or 3)] and their salts, and antiinflammatory agents, antirheumatic agents and antiulcer agents containing them as active ingredients. The compounds possess a strong antiinflammatory action while causing extremely reduced troubles of digestive organs which is a serious defect with conventional non-steroidal antiinflammatory agents, and possess an excellent antiulcer action as well.</p> |