发明名称 |
NONGLYCOSYLATED ANALOGS OF HUMAN COLONY STIMULATING FACTORS |
摘要 |
An analog human colony stimulating factor (hCSF) is disclosed, comprising a mutant amino acid sequence which is substantially homologous to the native sequence of an hCSF having at least one N-glycosylation site, wherein the mutant sequence comprises at least one amino acid substitution, deletion or insertion inactivating the N-glycosylation site. |
申请公布号 |
WO8903881(A1) |
申请公布日期 |
1989.05.05 |
申请号 |
WO1987US02799 |
申请日期 |
1987.10.30 |
申请人 |
IMMUNEX CORPORATION |
发明人 |
DEELEY, MICHAEL;PRICE, VIRGINIA, L.;URDAL, DAVID |
分类号 |
C12N15/09;C07K14/00;C07K14/52;C07K14/53;C07K14/535;C12N1/19;C12P21/02;C12R1/865;(IPC1-7):C12N15/00;C07K13/00;C12P19/34 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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