摘要 |
Compounds of formula :… …<CHEM>… in which… X is hydrogen, bromo, chloro, fluoro, iodo or any combination thereof up to four substituents; n is 0-5; and R is hydrogen or C1-4 alkyl; or a pharmaceutically acceptable salt or hydrate thereof, processes and intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy in inhibiting dopamine- beta -hydroxylase activity in mammals. |