| 摘要 |
<p>The invention concerns novel 1,3-dioxane ethers of the formula I, wherein R<Sup>1</Sup> includes alkyl, cycloalkyl, phenyl and phenylalkyl, R<Sup>2</Sup> and R<Sup>3</Sup> include hydrogen and alkyl, n is 1 or 2, m is 2, 3 or 4, p is zero, 1 or 2, and Z is carboxy or 1 (H)-tetrazol-5-yl, and pharmaceutically acceptable salts thereof, for use in conjunction with their pharmaceutical compositions in the treatment of certain pulmonary and/or vascular disorders. The invention also describes various processes and intermediates for the manufacture of the novel compounds.</p> |
