发明名称 |
Polyene compounds useful in the treatment of allergic responses |
摘要 |
Polyene compounds represented by the formula <IMAGE> in which R is H, lower alkyl of from 1 to 8 carbon atoms or aralkyl; R1 is H or lower alkyl of from 1 to 5 carbon atoms; and Y is carboxy, alkoxycarbonyl, alkenyloxycarbonyl, aralkoxycarbonyl, tetrazolyl or <IMAGE> wherein R is H, lower alkyl of from 1 to 8 carbon atoms or aralkyl; and pharmaceutically acceptable salts thereof. The foregoing compounds have been found active in regulating the formation of lipoxygenase and as such possess therapeutic value in the treatment of inflammatory conditions and allergic responses.
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申请公布号 |
US4621099(A) |
申请公布日期 |
1986.11.04 |
申请号 |
US19850778952 |
申请日期 |
1985.09.23 |
申请人 |
USV PHARMACEUTICAL CORPORATION |
发明人 |
LOEV, BERNARD;CHAN, WAN-KIT |
分类号 |
A61K31/165;A61K31/20;A61K31/215;A61K31/41;(IPC1-7):A61K31/19 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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