摘要 |
Improved bioconverting strain of Streptomyces thermotolerans useful in preparing tylosin esters and new antibacterial macrocin or lactenocin ester derivatives of the formula: <IMAGE> wherein R is formyl or hydroxymethyl; R1 is hydrogen, acetyl or propionyl; R2 is hydrogen or <IMAGE> and R3 is hydrogen, acetyl, propionyl, n-butyryl or isovaleryl; provided that one of R1 or R3 must be other than hydrogen. |