ACETYLENE DERIVATIVE AND TREATMENT FOR HYPERTENSION AND ANGINA

摘要

Acetylene compounds of the formula (I): wherein Y, R1, R2, R3, and R4 are as described herein, m is 0-3, n is 0-2 and Ar is pehnyl or an aromatic heterocycle are disclosed. The compounds possess antihypertensive and anti-anginal properties and may be used in the treatment of humans. Methods for the preparation and use of such acetylene compounds are also disclosed.