发明名称 |
GLYCOPROTEIN |
摘要 |
<p>TITLE OF THE INVENTION: NOVEL GLYCOPROTEIN Disclosed herein is a glycoprotein having molecular weight of 5,000 to 300,000 as determined by ultracentrifugal method; the weight ratio of protein moiety thereof determined by Lowry-Folin's method to saccharide moiety thereof determined by phenol - sulfuric acid method of in the range of 50/50 to 80/20; amino acid at N-end thereof consisting essentially of tyrosine, leucine or alanine; leucine-phenylalanine-valine as amino acid sequence at C-end thereof; the elementary composition consisting essentially of 35.2 to 49.3% of C, 4.8 to 8.0% of H, 4.3 to 12.3% of N, trace to 2.5% of S, trace to 1.2% of P and the balance of O; the isoelectric point of in the range of pH 2.5 to 5.0; and nucleic acid as a component. The novel glycoprotein has anti-tumour activity and a lectin-like activity.</p> |
申请公布号 |
CA1184899(A) |
申请公布日期 |
1985.04.02 |
申请号 |
CA19820395240 |
申请日期 |
1982.01.29 |
申请人 |
KUREHA KAGAKU KOGYO KABUSHIKI KAISHA |
发明人 |
YOSHIKUMI, CHIKAO;FUJII, TAKAYOSHI;FURUSHO, TAKAO;MATSUNAGA, KENICHI;OHARA, MINORU;KOBAYASHI, AKIRA |
分类号 |
C12P21/00;A61K36/07;A61K38/00;A61P35/00;C07K14/00;C07K14/37;C07K14/375;C07K14/41;C12N1/00;C12P1/06;C12P9/00;(IPC1-7):C07H21/00 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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