发明名称 |
PROCESS FOR THE REMOVAL OF THE FORMYL GROUP FROM N-FORMYL PEPTIDES AND ESTERS THEREOF |
摘要 |
A process for the removal of the formyl group in N-formylated peptides or their esters is described. The N-formyl compound is reacted with hydrazine or a substituted hydrazine of formula I: <IMAGE> at a pH between 1 and 3.5, keeping the pH constant during the reaction. The process is particularly useful for the preparation of aspartam. |
申请公布号 |
ZA8203232(B) |
申请公布日期 |
1983.03.30 |
申请号 |
ZA19820003232 |
申请日期 |
1982.05.11 |
申请人 |
PIERREL SPA |
发明人 |
GIOBBIO VINCENZO;ORNATO GIORGIO;BURACCHI LIVIO;MANGIA ALBERTO |
分类号 |
C07K1/06;C07C67/00;C07C231/00;C07C231/12;C07K1/12;C07K1/14;C07K5/075 |
主分类号 |
C07K1/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|