摘要 |
Title compds. I(R1,R2 = C12-20 n-alkyl, alkenyl; Y = C2-C4 alkylene, phenylenedimethylene; R3 = H, C2-4 alkyl, hydroxyalkyl) were prepd. Thus, [Me(CH2)15OCH2 2CHOH was treated with acrylonitrile and reduced over Raney Ni to give 54% [Me(CH2)15OCH2 2CHO(CH2)3NH2 (II). Mice infected with encephalomyocarditis virus and treated with 15mg II/kg i.p. had a relative survival rate of 61.
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