发明名称 1-(8-Quinolyl)-2-pyrrolidone and its pharmaceutical compositions
摘要 The compound of formula (I) <IMAGE> (I) and acid addition salts thereof are of value in medicine in the treatment or prophylaxis of pain, inflammation or fever. The compound and its salts may be administered alone or as a pharmaceutical formulation. The compound may be prepared by methods analogous to those known in the art or, for example, by cyclization of a 4-halo-N-(8-quinolyl)butyramide in the presence of aqueous sodium hydroxide and a phase transfer catalyst such as triethylbenzyl ammonium chloride.
申请公布号 US4366158(A) 申请公布日期 1982.12.28
申请号 US19800209426 申请日期 1980.11.24
申请人 BURROUGHS WELLCOME CO. 发明人 HODGSON, JR., GORDON L.
分类号 C07D401/04;A61K31/475;A61P25/04;A61P29/00;C07D215/40;(IPC1-7):C07D419/04 主分类号 C07D401/04
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