发明名称 |
N-[1,2,3,4,6,7,12,12 alpha -octahydro-2H-indolo(2,3 alpha )-quinolizinyl-2 beta -yl]alkane and benzyl sulfonamides and anti-hypertensive use thereof |
摘要 |
Indoloquinolizines of the formula (I) <IMAGE> (I) and their pharmaceutically acceptable acid addition salts [wherein R1 represents hydrogen, lower alkyl or lower aralkyl, R2 and R3 each represent hydrogen, halogen, lower alkoxy or lower alkyl, R4 represents hydrogen, halogen or lower alkyl and R5 represents lower alkyl or aryl] possess antihypertensive activity.
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申请公布号 |
US4358452(A) |
申请公布日期 |
1982.11.09 |
申请号 |
US19810253975 |
申请日期 |
1981.04.13 |
申请人 |
JOHN WYETH & BROTHER LIMITED |
发明人 |
OPALKO, ALBERT |
分类号 |
C07D471/14;(IPC1-7):A61K31/44;C07D471/04 |
主分类号 |
C07D471/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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