发明名称 Alpha-(acyl allophanamido) benzylpenicillins - broad spectrum antibiotics
摘要 <p>Penicillins of formula:- R'.NH.CO.NH.CO.NH. H.CO-(6-APA) and their salts and esters, R = opt. substd. phenyl; R' = acyl. The cpds. are broad spectrums antibiotics and are used as additives to animal foodstuffs. The cpds., their salts and esters are prepd. conventionally, e.g. by reaction of 6-APA, or an ester or salt of 6-APA with a reactive deriv. R'.NH.CO.NH.CO.NH. H.CO2H; also by reaction of an alpha-aminopenicillin of formula R. H.CO-(6-APA) with an N-methyl-N-nitroso-N'-acylbiuret.</p>
申请公布号 FR2140115(A1) 申请公布日期 1973.01.12
申请号 FR19720019474 申请日期 1972.05.31
申请人 BEECHAM GROUP LTD 发明人
分类号 C07D499/00;C07D499/68;(IPC1-7):61K21/00;07D99/00 主分类号 C07D499/00
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