DITHIENYL ALKYL AMINES AND PROCESS FOR THEIR PRODUCTION

摘要

The present invention provides compounds of the general formula I wherein has either the structure or the structure , Alk represents a straight or branched C1-C5-alkylene group and Y a C3-C7-cycloalkyl radical, a methylenedioxy-benzyl radical, a benzyl radical which is singly, doubly or triply substituted by C1-C4-alkoxy groups, or it represents a straight or branched C1-C6-alkyl radical substituted by a di-C1-C4-alkyl-amino group, a morpholino group, or it represents the radical wherein R represents a C1-C4-alkyl group and the hydroxyl group can also be acylated by a C2-C6-alkanoyl group or wherein the group -NHY represents the radical and R' represents a phenyl radical, a phenyl radical, which is Aingly or doubly substituted by C1-C4-alkyl groups, C1-C4 alkoxy groups or halogen atoms, a C1-C6-alkyl radical, a C1-C4-oxy-alkyl radical or a phenyl-C1-C4-alkyl radical, which can also be substituted in the phenyl ring by 1 to 3 C1-C4-alkoxy groups or the radical -NH-CH(R)-CH(OH)-C6H5 (wherein R has the meaning defined above) when Alk consists of 2 to 5 carbon atoms or a pharmaceutically acceptable salt thereof. These compounds are pharmaceutically effective, particularly in the case of heart and circulation disorders. In particular, they cause an increase of the peripheral and cerebral blood flow.