FREMGANGSMÅDER OG MIDLER TIL MODULERING AF LIPIDBIOSYNTESE VED MÅLRETNING AF FLERE ENZYMER MOD SUBORGANELDOMÆNER

摘要

Methods and means are provided to alter lipid biosynthesis in eukaryotic organisms by targeting at least two different polypeptides involved in fatty acid or lipid metabolism towards a similar or the same subdomain of an organelle, such as the endoplasmatic reticulum (ER), through fusion of the polypeptides with a similar or the same heterologous polypeptide targeting the chimeric fusion polypeptide to the mentioned subdomain.