摘要 |
<p>Cyclopentane derivatives useful as intermediates in the preparation of 15-substituted-.omega.-pentanorprostaglandins and processes for the preparation thereof, the said cyclopentane derivatives having the formula: ...I wherein A is cycloalkyl of from three to ten carbon atoms, 1-adamantyl, 2-norbornyl, 2-(1,2,3,4-tetrahydronaphthyl), 2indanyl or substituted 2-indanyl wherein the substitutent is halo, trifluoromethyl, lower alkyl or lower alkoxy; Q is hydrogen, p-biphenylcarbonyl or 2-tetrahydro-pyranyl; n is an integer from 0 to 5; Y is =0, or ; Z is a single bond or a trans double bond, and X is =0 or , wherein Q' is hydrogen or 2-tetrahydropyranyl and R is hydrogen or lower alkyl, with the proviso that when Q' is 2-tetrahydropyranyl Q is also 2-tetrahydropyranyl and when Q is p-biphenylcarbonyl and X and Y are =0, Z is a trans double bond.</p> |