ALFA-SULFOFONYLETTIKSYRADERIVAT TILL ANVENDNING SONM MELLANPRODUKT VID FRAMSTELLNING AV MOTSVARANDE ALFA-SULFOBENSYLPENICILLINER

摘要

alpha -Sulfophenylacetic acid derivatives of the general formula: -CHCOOH ¦ SO3R (wherein R is a substituted or unsubsituted primary alcohol, cyclic alcohol or phenol compound residue), which are of value as intermediates of antibacterial agents, are selectively produced in a high yield by bringing a diester compound of the general formula: CH3 ¦ -CHCOO-C-CH3 ¦¦ SO3RCH3 (wherein R has the same meaning as defined above) into contact with a strong acid.