摘要 |
1533290 Pharmaceutical compositions containing 2-alkoxy-4-amido-thiazoles JOHN WYETH & BRO Ltd 2 June 1977 [10 June 1976] 24162/76 Heading A5B [Also in Division C2] Pharmaceutical compositions which comprise a compound I wherein R is H, C 1-6 alkyl or COR<SP>3</SP>, R<SP>3</SP> is H, C 1-5 alkyl (optionally substituted by one or more selected from Cl, Br, CF 3 , CH 3 O, C 2 H 5 O, NH 2 , C 1-6 alkylamino, di C 1-6 alkylamino, OH or CN), C 2-5 alkenyl or alkynyl, C 1-5 -perfluoroalkyl or C 3-5 cycloalkyl, R<SP>1</SP> is H or C 1-6 alkyl and R<SP>2</SP> is C 1-6 alkyl, with the usual excipients show anti-ulcer and anti-secretory activity when administered orally or rectally. The compositions may also contain an antacid such as aluminium hydroxide and magnesia.
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