| 发明名称 |
OREXIN-CONTROL OF BONE FORMATION AND LOSS |
| 摘要 |
The use of orexin 1 receptor antagonists and/or orexin 2 receptor agonists thereof in the treatment of bone loss diseases is described. Such conditions include osteoporosis, rheumatoid arthritis and other bone wasting diseases. |
| 申请公布号 |
US2016250224(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201415024354 |
申请日期 |
2014.09.24 |
| 申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
WAN Yihong |
| 分类号 |
A61K31/551;A61K31/472;A61K9/00;A61K31/454 |
主分类号 |
A61K31/551 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of increasing bone mass and/or volume in a subject comprising:
(a) identifying a patient in need of increased bone mass and/or volume; and (b) administering to said subject an agonist of orexin receptor 2 and/or an antagonist of orexin receptor 1. |
| 地址 |
Austin TX US |
