| 发明名称 |
Immunkonjugater II |
| 摘要 |
The invention relates to new immunoconjugates comprising of a monoclonal antibody or a fragment thereof specific for the human EGF-receptor molecule and a member of the chemokine family, preferably selected from the C-X-C family, e.g. Interleukin-8 (IL-8). The immunoconjugates induce cytotoxic and chemotactic activity and are suitable for a targeted tumor therapy.
|
| 申请公布号 |
NO953650(D0) |
申请公布日期 |
1995.09.15 |
| 申请号 |
NO19950003650 |
申请日期 |
1995.09.15 |
| 申请人 |
MERCK PATENT GMBH |
发明人 |
HOLZER, WOLFGANG;HOEGEN, ILKA VON;STRITTMATTER, WOLFGANG;MATZKU, SIEGFRIED |
| 分类号 |
C12N15/02;A61K38/00;A61K38/19;A61K39/385;A61K39/395;A61K39/44;A61K47/48;A61P35/00;A61P43/00;C07K14/485;C07K14/52;C07K14/54;C07K14/705;C07K14/715;C07K16/00;C07K16/28;C07K16/46;C12N15/62;C12P21/08;C12R1/91;(IPC1-7):A61K |
主分类号 |
C12N15/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
