发明名称 Subst ureidophenoxy 2-hydroxy-3-substd aminopropanes - - beta adrenergic blocking agents
摘要 <p>Title cpds. are of formula (I): and salts of (I) (where R1 and R2 are 1-6C unbranched alkyl, 3-8C branched alkyl, 3-6C alkenyl, or 3-7C cycloalkyl, and R1 may also be H). (I) can be prepd. by (a) condensing an aminophenoxypropane with an isocyanate R2NCO or a cpd. R2NHCOR4 where R4 is 1-4C O-alkyl, 1-4C S alkyl, opt. substd. O Ph, opt. substd. S Ph, NH2, NHR2, NHNH2, or hal; (b) condensing an amine R2NH with an isocyanatophenoxypropane; (c) oxidising a corresp. thioureido analogue; (d) condensing a ureidophenol with an epoxypropane or propylester, etc.</p>
申请公布号 FR2113982(A1) 申请公布日期 1972.06.30
申请号 FR19710040829 申请日期 1971.11.15
申请人 ARZNEIMITTELWERK DRESDEN,DL 发明人 ECKARDT R;CARSTENS E;FEMMER K
分类号 C07C275/14;A61K31/17;C07C273/18;C07C275/34;(IPC1-7):61K27/00;07C127/00 主分类号 C07C275/14
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