发明名称 |
Therapeutic delivery using compounds self-assembled into high axial ratio microstructures |
摘要 |
Therapeutic agents comprising plural therapeutic compounds self assembled into high axial ratio microstructures are described. The threapeutic compounds satisfy the formula HARFM-Th, wherein HARFM is a high axial ratio forming material and Th is a therapeutic associated with the HARFM. The therapeutic agent also can satisfy the formula HARFM-S-Th, wherein S is a spacer. Release of the therapeutic by the agent generally follows either 0-order kinetics or psuedofirst order kinetics. A method for delivering drugs to animals or persons also is described. The method comprises administering an effective amount of a therapeutic self-assembled into an HAR microstructure to the animal or person.
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申请公布号 |
US5851536(A) |
申请公布日期 |
1998.12.22 |
申请号 |
US19960752848 |
申请日期 |
1996.11.21 |
申请人 |
UNIVERSITY OF WASHINGTON |
发明人 |
YAGER, PAUL;GELB, MICHAEL H.;CARLSON, PAUL A.;LEE, KYUJIN C.;LUKYANOV, ANATOLY N.;GOLDSTEIN, ALEX S. |
分类号 |
A61K47/48;(IPC1-7):A61K9/00;A61K9/127 |
主分类号 |
A61K47/48 |
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