发明名称 |
Postsurgical adhesion barrier of carboxymethylchitosan and carboxymethylcellulose and method for preparation thereof |
摘要 |
<p>The present invention relates to a postsurgical adhesion barrier of carboxymethylchitosan, carboxymethylchitosan/carboxymethylcellulose cross-linked with multivalent ions and a method for preparation of the barrier. The method of preparation comprises: preparing a carboxymethxylchitosan polymer aqueous solution and carboxymethylcellulose polymer aqueous solution in purified water respectively, applying the carboxymethxylchitosan solution, or a mixed solution of carboxymethxylchitosan and carboxymethylcellulose with certain weight ratio on a smooth plate, drying the plate with the applied polymer aqueous solution to obtain a film thereon, socking the dried film on the plate in a aqueous solution of cross-linking agent selected from Ca<++> ion, Fe<+++> ion, a mixture of Ca<++> and Fe<+++>, or a mixture of Ca<++> and Al<+++> to complete cross-linking reaction, and drying and detaching the cross-linked film. The obtained postsurgical adhesion barrier is biocompatible and bioresorbable.</p> |
申请公布号 |
EP1508344(A1) |
申请公布日期 |
2005.02.23 |
申请号 |
EP20040019723 |
申请日期 |
2004.08.19 |
申请人 |
DALIAN YONGXING MEDICAL MATERIAL, CO. LTD. |
发明人 |
ZHANG, LIANZHONG;WANG, SHUQIN;FENG, BOZHI |
分类号 |
A61L31/04;(IPC1-7):A61L31/04 |
主分类号 |
A61L31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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