发明名称 Dopamine receptor ligands and imaging agents.
摘要 <p>Novel CNS dopamine D-1 receptors, such as the compound (+/-)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-(4 min -[&lt;1&gt;&lt;2&gt;&lt;5&gt;I]iodophenyl)-1H- 3- be nz az epine-7-ol, are disclosed. These compounds are useful as imaging agents for D-1 receptors in the human brain and exhibit good brain retention and in vivo stability.</p>
申请公布号 EP0391554(A1) 申请公布日期 1990.10.10
申请号 EP19900302806 申请日期 1990.03.15
申请人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 KUNG, HANK F.
分类号 A61K51/00;A61K51/04;C07D223/16;C07F3/14;C07F7/08;C07F7/10;C07F7/22;G01N33/50 主分类号 A61K51/00
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