摘要 |
Disclosed is a peptide derivative of the formula: wherein A1, A2, R3, R4, R5, B and X2 are defined herein. Also disclosed is a drug for treating hypertension, pulmonary hypertension, Raynaud's disease, acute renal failure, myocardial infarction, angina pectoris, cerebral infarction, cerebral vasospasm, arteriosclerosis, asthma, endotoxin shock, endotoxin-induced multiple organ failure or disseminated intravascular coagulation, and/or cyclosporin-induced renal failure or hypertension, which drug is a peptide derivative of the formula (I) or a pharmaceutically-acceptable salt thereof.
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申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIKAWA, KIYOFUMI;FUKAMI, TAKEHIRO;HAYAMA, TAKASHI;NIIYAMA, KENJI;NAGASE, TOSHIO;MASE, TOSHIAKI;FUJITA, KAGARI;IHARA, MASAKI;IKEMOTO, FUMIHIKO;YANO, MITSUO |