摘要 |
<p>The present invention relates to certain novel quinolone compounds of the present invention represented by formula (I) and novel process for preparing same, wherein X is a nitrogen atom or a C-Y group wherein Y is a hydrogen, fluorine, chlorine or bromine atom or a methoxy or methyl group; R1 is a C1-6 alkyl group optionally substituted with a halogen atom or a hydroxy radical, an alkenyl group, a C3-6 cycloalkyl group, a phenyl group substituted with a halogen atom or a divalent group of -OCH2*CH(CH3)-, -SCH2*CH2- or -SCH2*CH(CH3)- which forms an oxazine or thiazine ring together with the nitrogen atom to which R1 is attached and with X wherein X is C-Y; R2 is a hydrogen atom, a carboxy protecting group or a pharmaceutically acceptable metal or organic cation; R3 and R4, which may be the same or different, are a hydrogen atom, a lower alkyl group, an acyl group or a nitrogen protecting group metabolizable in vivo; Z is a hydrogen or halogen atom, an amino, hydroxy or methyl group; and n is 1 to 3.</p> |