Methods of treatment using ciliary neurotrophic factor

摘要

The present invention relates to methods of treatment of neurological disorders comprising administering ciliary neurotrophic factor (CNTF) to a patient in need of such treatment, as well as to methods of diagnosing structural damage to the nervous system comprising detecting increased levels of CNTF in a patient's tissue or body fluid. In non-limiting embodiments, the present invention provides for methods of treating upper motor neuron disorders and disorders that involve the subependymal zone, and for methods of diagnosing nervous system damage comprising detecting increased levels of CNTF in a patient's cerebrospinal fluid.