| 摘要 |
Disclosed are intermediates compounds 5 and 8 that can be used to prepare 4-oxoquinolone compounds of formula 13 having useful integrase inhibiting properties. The chemical names of the synthesised compounds and intermediates are: 1-chloro-3-(2,4-dimethoxybenzyl)-2-fluorobenzene (5) 1-[5-(3-chloro-2-fluoro-benzyl)-2,4-dimethoxyphenyl]-ethanone (8) ethyl 3-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxyphenyl)-3-oxopropanoate (9) |
