发明名称 |
A PROCESS FOR PREPARATION OF INSULIN COMPOUNDS |
摘要 |
The present invention relates to the preparation of insulin compounds including their analogs or derivatives thereof from their corresponding precursor forms by a one step enzymatic reaction involving the combinatorial and concurrent use of optimal quantities of trypsin and carboxypeptidase B that work synergistically directing the reaction in a controlled manner to avoid production of random undesired byproducts. Particularly, the enzymatic conversion reactions of the instant invention offer advantages of reduction in the number operational steps, higher yield and purity of the desired end products. |
申请公布号 |
PL2307441(T3) |
申请公布日期 |
2016.09.30 |
申请号 |
PL20050088767T |
申请日期 |
2008.09.19 |
申请人 |
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发明人 |
HAZRA PARTHA;SATHYANARAYANA SRIKANTH GOLLARAHOSAHALLI;SREENIVAS SUMA;SHIVARUDRAIAH MANJUNATH HADAVANAHALLI;SASTRY KEDARNATH NANJUND;IYER HARISH |
分类号 |
C07K1/12;C07K14/62;C12P21/06 |
主分类号 |
C07K1/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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