发明名称 METHOD FOR DETERMINING ORGANISM SENSITIVITY TO PHARMACEUTICAL PREPARATIONS AND STOMATOLOGICAL MATERIALS
摘要 FIELD: medicine. ^ SUBSTANCE: method involves applying material sample to gingival, counting meutrophils available in oral lavage taken before and after bringing mucous membrane in contact with the material, centrifuging, determining meutrophil emigration level in oral cavity and meutrophil shift index. Neutrophils are counted by staining peroxidase with chromogen solution. Neutrophil shift index is determined from their optical density using formula SHIFT INDEX =(optical lavage density after having treated with the material)/(optical lavage density before having treated with the material). Neutrophil shift index being within 0.75 to 1.5, organism sensitivity to substance under treatment is considered to be normal. ^ EFFECT: accelerated test process.
申请公布号 RU2241995(C1) 申请公布日期 2004.12.10
申请号 RU20040107547 申请日期 2004.03.16
申请人 发明人 KOZACHENKO NADEZHDA VENIAMINOVNA;LEBEDEV K.A.;MAKSIMOVSKIJ JU.M.;MITRONIN A.V.;PONJAKINA I.D.;STROKINA OL'GA MIKHAJLOVNA
分类号 G01N33/48;G01N33/52 主分类号 G01N33/48
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