Biologically active amines

摘要

There are disclosed compounds of the formula (I): Ar-CH2CH2-NH-CR<1>R<2>-X-Y in which Ar represents a group alpha , X represents a C1-12 alkylene chain optionally interrupted or terminated by one or more groups selected from -S-, -SO-, -SO2-, -O-, CR<6>R<7>, phenylmethyne, -NH-, -CONH-, -NHCO- and -NHCONH-, Y represents an optionally substituted aryl or cycloalkyl group, R<1>, R<2>, R<5>, R<6>, R<7> and R<8> each independently represent hydrogen or alkyl C1-6, and R<3> and R<4> represent hydrogen, or R<3> and R<4> together form a group -S-, -NR<8>- or -CH2-, and pharmaceutically acceptable derivatives thereof. Processes for their production and pharmaceutical compositions and methods of treatment involving their use are also described.