发明名称 Use and derivatives of imidazole their preparation process the intermediates obtained their use as medicaments and the pharmaceutical compositions containing them
摘要 PCT No. PCT/FR95/01034 Sec. 371 Date Jan. 31, 1997 Sec. 102(e) Date Jan. 31, 1997 PCT Filed Aug. 1, 1995 PCT Pub. No. WO96/04276 PCT Pub. Date Feb. 15, 1996The invention relates to the new use and the new products of formula (I): <IMAGE> (I) in which: R1=represents hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, formyl, cycloalkyl, optionally interrupted by heteroatoms, R2, R3 represent in particular halogen, mercapto, acyl, carboxy, nitro, cyano, amino, carbamoyl, R4, -OR4 with R4 representing in particular hydrogen, alkyl, alkenyl, alkynyl, acyl, amino, -(CH2)m1-S(O)m2-X-R10 with m1=0 to 4, m2=0 to 2, X represents a single bond or -NH-, -NH-CO-, -NH-CO-NH-, and R10 represents alkyl, alkenyl or aryl, and Y represents optionally substituted aryl, these products being in all the isomer forms and the salts, as medicaments.
申请公布号 ZA9506453(B) 申请公布日期 1996.08.05
申请号 ZA19950006453 申请日期 1995.08.02
申请人 ROUSSEL UCLAF. 发明人 BERTRAND HECKMANN;JEAN-PAUL VEVERT;JIDONG ZHANG
分类号 A61K31/415;A61K31/4178;A61K31/422;A61P3/02;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P43/00;C07D233/84;C07D405/06 主分类号 A61K31/415
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