Drug delivery balloon apparatus and methods for use

摘要

A drug delivery balloon apparatus is disclosed herein, comprising: (a) at least two lumens, comprising a first lumen and a second lumen, (b) a balloon inflation port in communication with the first lumen, (c) a drug delivery port in communication with the second lumen, (d) a guidewire port in communication with either the second lumen or a third lumen, (e) an occlusion balloon, (f) a drug delivery balloon having an outer surface with a plurality of grooves, where the occlusion balloon is disposed between the drug delivery balloon and the balloon inflation port, and the occlusion and drug delivery balloons are in communication with the first lumen, (g) one or more drug delivery channels extending the length of the second lumen, and (h) one or more drug delivery ducts extending from the one or more drug delivery channels to an exterior surface of the second lumen.

主权项

1. A drug delivery balloon apparatus comprising:
at least two lumens, comprising a first lumen and a second lumen; a balloon inflation port in fluid communication with the first lumen; a drug delivery port in fluid communication with the second lumen; a guidewire port in fluid communication with the second lumen, wherein the second lumen is configured to receive both a guidewire and a drug solution; an occlusion balloon; a drug delivery balloon, wherein an outer surface of the drug delivery balloon defines a plurality of grooves each extending from a first end of the drug delivery balloon to a second end of the drug delivery balloon, wherein the plurality of grooves are spiraled, helical, or sinusoidal, wherein the occlusion balloon is disposed between the drug delivery balloon and the balloon inflation port, and wherein the occlusion balloon and the drug delivery balloon are in fluid communication with the first lumen; one or more drug delivery channels extending the length of the second lumen; and one or more drug delivery ducts extending from the one or more drug delivery channels to an exterior surface of the second lumen, and wherein the one or more drug delivery ducts are defined only in a portion of the second lumen that is disposed between the occlusion balloon and the drug delivery balloon.