METHODS OF DIAGNOSING HEPATOCELLULAR CARCINOMA AND PANCREATIC CANCER

摘要

Disclosed herein are biomarkers for hepatocellular carcinoma and pancreatic cancer. The biomarkers may be laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CA19-9, or combinations thereof. Also disclosed herein are methods of diagnosing, prognosing, classifying risk, and monitoring progression of hepatocellular carcinoma or pancreatic cancer by the detecting the level of laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CA19-9, or combinations thereof.

主权项

1. A method of diagnosing hepatocellular carcinoma (HCC) in a subject in need thereof, the method comprising:
(a) obtaining a biological sample from the subject; (b) determining a level of laminin gamma 2 monomer in the biological sample; (c) comparing the level of laminin gamma 2 monomer to a reference level of laminin gamma 2 monomer; and (d) identifying the subject as having HCC when the level of laminin gamma 2 monomer is greater than the reference level of laminin gamma 2 monomer.