发明名称 PYRIDINE DERIVATIVE PIM KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE PREPARATION
摘要 A PIM kinase inhibitor, a preparation method therefor, and application thereof. A structural formula thereof is a compound as shown in a general formula (I). The PIM kinase inhibitor comprises a stereoisomer, a tautomer, and pharmaceutical salt of the compound in the formula (I). The compound has an obvious inhibiting function on the activity of kinase. The PIM kinase inhibitor can be used for preparing medicine for treating or preventing cancer, autoimmune diseases, and anaphylactic reaction diseases or resisting organ transplantation rejection, and the like. A great clinic application value is obtained.
申请公布号 WO2017045615(A1) 申请公布日期 2017.03.23
申请号 WO2016CN99044 申请日期 2016.09.14
申请人 JIKAI BIOSCIENCES, INC 发明人 GE, Yu
分类号 C07D401/12;A61K31/444;A61P35/00;C07D401/14 主分类号 C07D401/12
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