POLYANION FOR IMPROVED NUCLEIC ACID AMPLIFICATION

摘要

The present invention is directed to a novel chemical compound comprising the structure [X x - (CH2) m - Phosphate - Yy ] n, characterized in that 3 <= m <= 6, 30 <= n <= 60, each x and y is independently from each other 0 or 1, each X and Y is independently from each other any photometrically measurable entity; provided that the terminal X can also be an -OH group or a Phosphate group, and further provided that the terminal Y can also be an - -OH group. Such a compound can be used as a suitable hot start additive for PCR based amplification of nucleic acids.