发明名称 |
細胞ベースの抗癌組成物ならびに当該物の製造方法および使用方法 |
摘要 |
Isolated pluralities of T cells which recognize at least one epitope of a mucosally restricted antigen and pharmaceutical compositions comprising the same are disclosed. Methods of making a plurality of T cells that recognize at least one epitope of a mucosally restricted antigen are also disclosed. Methods of treating an individual who has been diagnosed with cancer of a mucosal tissue or preventing such cancer in an individual at elevated risk are disclosed as are nucleic acid molecules that comprise a nucleotide sequence that encode proteins that recognize at least one epitope of a mucosally restricted antigen and T cells comprising such nucleic acid molecules. |
申请公布号 |
JP5955771(B2) |
申请公布日期 |
2016.07.20 |
申请号 |
JP20120535411 |
申请日期 |
2010.10.22 |
申请人 |
トーマス・ジェファーソン・ユニバーシティThomas Jefferson University |
发明人 |
スコット・エイ・ウォルドマン;アダム・イー・スヌーク |
分类号 |
C12N15/09;A61K35/17;A61K39/00;A61P35/00;C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|