| 发明名称 |
Methods for Expressing a Polynucleotide of Interest in the Retina of a Subject |
| 摘要 |
The present invention relates to methods for expressing a polynucleotide of interest in the retina of a subject. In particular, the present invention relates to a method for expressing a polynucleotide of interest in the retina of a subject comprising the step consisting of injecting into the vitreous an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression. |
| 申请公布号 |
US2016144057(A1) |
申请公布日期 |
2016.05.26 |
| 申请号 |
US201414900350 |
申请日期 |
2014.06.27 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ DE LA RECHERCHE MÉDICALE) ;UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6) ;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
Dalkara Deniz;Rendon Fuentes Alvaro;Sahel Jose Alain;VACCA Ophelie |
| 分类号 |
A61K48/00;A61K38/46;A61K9/00;C12N15/113;C12N7/00;A61K31/713 |
主分类号 |
A61K48/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for expressing a polynucleotide of interest in the retina of a subject comprising the step of injecting into the vitreous of said subject an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression. |
| 地址 |
Paris FR |
