| 发明名称 |
Compositions and Methods for Treatment of Cancer |
| 摘要 |
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. |
| 申请公布号 |
US2016130355(A1) |
申请公布日期 |
2016.05.12 |
| 申请号 |
US201614996953 |
申请日期 |
2016.01.15 |
| 申请人 |
The Trustees of the University of Pennsylvania |
发明人 |
June Carl H.;Levine Bruce L.;Porter David L.;Kalos Michael D.;Milone Michael C. |
| 分类号 |
C07K16/28;C07K14/725;C12N7/00;C07K14/525;A61K48/00;C07K16/30;C07K14/705 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
Philadelphia PA US |
