发明名称 |
Method and System for Non-Invasive Computation of Hemodynamic Indices for Coronary Artery Stenosis |
摘要 |
A method and system for non-invasive hemodynamic assessment of coronary artery stenosis based on medical image data is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient. Patient-specific boundary conditions of a computational model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements of the coronary arteries. Blood flow and pressure in the coronary arteries are simulated using the computational model of coronary circulation and the patient-specific boundary conditions and coronary autoregulation is modeled during the simulation of blood flow and pressure in the coronary arteries. A wave-free period is identified in a simulated cardiac cycle, and an instantaneous wave-Free Ratio (iFR) value is calculated for a stenosis region based on simulated pressure values in the wave-free period. |
申请公布号 |
US2015324962(A1) |
申请公布日期 |
2015.11.12 |
申请号 |
US201514689083 |
申请日期 |
2015.04.17 |
申请人 |
Siemens Aktiengesellschaft |
发明人 |
Itu Lucian Mihai;Sharma Puneet;Redel Thomas;Georgescu Bogdan |
分类号 |
G06T7/00;A61B5/02;A61B5/00 |
主分类号 |
G06T7/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method for hemodynamic assessment of a coronary artery based on medical image data of a patient, comprising:
extracting patient-specific anatomical measurements of the coronary arteries from medical image data of a patient; calculating patient-specific boundary conditions of a computational model of coronary circulation representing the coronary arteries based on the patient-specific anatomical measurements of the coronary arteries; simulating blood flow and pressure in the coronary arteries using the computational model of coronary circulation and the patient-specific boundary conditions and modeling coronary autoregulation during the simulation of blood flow and pressure in the coronary arteries; and calculating a hemodynamic index for at least one region in the coronary arteries based on the simulated blood flow and pressure. |
地址 |
Munich DE |