发明名称 |
NITROGENATED BICYCLIC AROMATIC HETEROCYCLIC COMPOUND |
摘要 |
[Problem] On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. [Means for Solution] It was found that a nitrogen-containing bicyclic heterocyclic compound has the excellent cathepsin S inhibitory effect, thereby completing the invention. The compound of the present invention has the cathepsin S inhibitory effect, and can be used as an agent for preventing and/or treating autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like. |
申请公布号 |
EP2840083(A4) |
申请公布日期 |
2015.10.28 |
申请号 |
EP20130777902 |
申请日期 |
2013.04.17 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
NAKAJIMA, YUTAKA;IMADA, SUNAO;TAKASUNA, YUJI;AOYAMA, NAOHIRO;NIGAWARA, TAKAHIRO;SHIRAKAMI, SHOHEI;SHIRAI, FUMIYUKI;SATO, JUNJI;NAKANISHI, KEITA;KUBO, KAORI |
分类号 |
C07D487/04;A61K31/519;A61K31/5377;A61P37/06;A61P37/08;A61P43/00;C07D473/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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