| 发明名称 | Peptide specific for ovarian cancer and applications | ||
| 摘要 | The present invention provides a novel peptide with high specificity for recognition of ovarian cancer. The peptide is selected using M13 phage display library and epithelial-enrich-conjugated magnetic beads. Only a small amount of the peptide is required to establish over 80% binding activity to ovarian cancer comparing to low binding activities to other cancers, showing high specificity for ovarian cancer. Thus the peptide of the present invention can be effective in early detection of ovarian cancer. | ||
| 申请公布号 | US9170261(B2) | 申请公布日期 | 2015.10.27 |
| 申请号 | US201414185108 | 申请日期 | 2014.02.20 |
| 申请人 | NATIONAL TSING HUA UNIVERSITY | 发明人 | Lee Gwo-Bin;Wang Chih-Hung |
| 分类号 | C07K17/14;G01N33/574;G01N33/543;C07K7/08 | 主分类号 | C07K17/14 |
| 代理机构 | WPAT, P.C. | 代理人 | WPAT, P.C. ;King Anthony |
| 主权项 | 1. An isolated ovarian cancer-targeting peptide, comprising an amino acid sequence of SEQ ID NO: 1 encoded by a nucleotide sequence of SEQ ID NO: 2. | ||
| 地址 | Hsinchu TW | ||